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Paulette D. Chandler, MD, MPH

Assistant Professor of Medicine, Harvard Medical School
Associate Physician, Brigham and Women’s Hospital

Paulette Chandler, MD, MPH is an Assistant Professor of Medicine at Harvard Medical School in Boston, Massachusetts. She is a primary care physician at the Brigham and Women’s Hospital, where she is Associate Epidemiologist in the Division of Preventive Medicine. She also has an appointment in the Division of General Internal Medicine and Primary Care. Dr. Chandler received her undergraduate degree from Princeton University, and her medical degree from Duke Medical School. She completed an internal medicine residency at Brigham and Women’s Hospital and a community health fellowship at the Harvard T. H. Chan School of Public Health, where she also obtained a Masters in Public Health (Clinical Effectiveness). She is board certified in internal medicine. Dr. Chandler’s research focuses on understanding the connection between nutrition, novelbiomarkers generated through the “-omics” technology, and cancer prevention. Her current American Cancer Society Mentored Research Scholar Grant in Applied and Clinical Science focuses on uncovering links between nutrition and colorectal cancer risk by using metabolomics to measure a wide profile of circulating small-molecule metabolites to comprehensively evaluate metabolic pathways linked to risk factors that may be more prevalent in those who eat a Western versus Mediterranean diet, with the goal of prompting new therapies and dietary recommendations. Dr. Chandler’s clinical interests include nutrition, cancer and diabetes prevention, and women’s health. She is passionate about educating the public on the power of healthy lifestyle choices for preventing disease and promoting wellness. She is actively involved with several randomized clinical trials and observational studies and serves on the Cancer Endpoints Committee of the VITamin D and OmegA-3 Trial (VITAL) and COcoa Supplement and Multivitamin Outcomes Study(COSMOS) and serves as the Medical/Safety Officer for the COSMOS and the Magnesium and Blood Pressure clinical trial.

MD: Duke University School of Medicine
MPH: Harvard T.H. Chan School of Public Health

  1. Chandler PD, Scott JB, Drake BF, Ng K, Manson JE, Rifai N, Chan AT, Bennett GG, Hollis BW, Giovannucci EL, Emmons KM, Fuchs CS. Impact of vitamin D supplementation on inflammatory markers in African Americans: results of a four-arm, randomized, placebo-controlled trial. Cancer Prev Res (Phila). 2014 Feb;7(2):218-25. PubMed PMID: 24327720; PubMed Central PMCID: PMC4038929
  2. Chandler PD, Giovannucci EL, Scott JB, Bennett GG, Ng K, Chan AT, Hollis BW, Emmons KM, Fuchs CS, Drake BF. Null association between vitamin D and PSA levels among black men in a vitamin D supplementation trial. Cancer Epidemiol Biomarkers Prev. 2014 Sep;23(9):1944-7. PubMed PMID: 24974387; PubMed Central PMCID: PMC4167903.
  3. Chandler PD, Akinkuolie AO, Tobias DK, Lawler PR, Li C, Moorthy MV, Wang L, Duprez DA, Jacobs DR, Glynn RJ, Otvos J, Connelly MA, Post WS, Ridker PM, Manson JE, Buring JE, Lee IM, Mora S. Association of N-Linked Glycoprotein Acetyls and Colorectal Cancer Incidence and Mortality. PLoS One. 2016;11(11):e0165615. PubMed PMID: 27902713; PubMed Central PMCID: PMC5130185.
  4. Chandler PD, Tobias DK, Wang L, Smith-Warner SA, Chasman DI, Rose L, Giovannucci EL, Buring JE, Ridker PM, Cook NR, Manson JE, Sesso HD. Association between Vitamin D Genetic Risk Score and Cancer Risk in a Large Cohort of U.S. Women. Nutrients. 2018 Jan 9;10(1)PubMed PMID: 29315215; PubMed Central PMCID: PMC5793283.
  5. Tabung FK, Liang L, Huang T, Balasubramanian R, Zhao Y, Chandler PD, Manson JE, Cespedes Feliciano EM, Hayden KM, Van Horn L, Clish CB, Giovannucci EL, Rexrode KM. Identifying metabolomic profiles of inflammatory diets in postmenopausal women. Clin Nutr. 2019 Jun 17;PubMed PMID: 31255351; PubMed Central PMCID: PMC6918009.

Full Listing of Publications

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