My research interests are focused on the epidemiology of cardiovascular disease (particularly stroke) and neurologic disease (especially those with a vascular component) with the goal of identifying ways to reduce the morbidity burden associated with stroke, migraine, and cognitive decline. In an effort to reduce the morbidity burden from cardiovascular and neurologic disease and understand the underlying biology behind cardiovascular and neurologic disease morbidity, my research has focused on four main areas: (1) the functional consequences of migraine, (2) elucidating factors that ameliorate the impact of cognitive impairment on incident disability, (2) risk factors for functional outcomes from stroke, and (4) risk factors for overall cerebrovascular disease burden in the brains of ischemic stroke patients. In addition to my research activities, I am actively involved in teaching activities at the Harvard T.H. Chan School of Public Health and Harvard Medical School.